Different mechanisms of enzymatic action
Molecular enzymology - Enzymatic catalysis
Article REF: PHA1504 V1
Different mechanisms of enzymatic action
Molecular enzymology - Enzymatic catalysis

Authors : Julien DUMOND, Serge KIRKIACHARIAN

Publication date: April 10, 2025 | Lire en français

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2. Different mechanisms of enzymatic action

2.1 Enzymatic reaction to one substrate

The simplest enzymatic reaction is catalyzed by a single enzyme that converts one substrate into one product. The reaction is dependent on the concentration of substrate and product over time, and on the equilibrium to be reached.

The nature of the enzyme (with coenzyme or release of several products) can generate irreversible reactions under given conditions.

In the case of a simple mechanism, the work of Michaelis and Menten, followed by Briggs and Haldane, has made it possible to establish the kinetics of the reaction transforming one substrate into one product

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