6. Antifungal activity of nanomaterials

Numerous teams have studied the antibacterial effects of nanoparticles, but there are few studies concerning antifungal effects. Unlike bacteria, which are single-cell prokaryotic organisms, fungi are eukaryotic organisms and can be unicellular or multicellular. The number of drugs available to treat fungal diseases is relatively limited, and there is a growing demand for the development of new treatments. The antifungal drugs currently used to treat fungal diseases, such as those caused by C. albicans, are directed against multiple targets: the fungal wall, plasma membranes, DNA, RNA, proteins involved in ergosterol synthesis, etc. The most widely used drugs to treat fungal diseases are those used to treat C. albicans. The drugs most commonly used to treat fungal infections are polyenes and azoles. The literature is full of evidence of the resistance of fungal strains to these two groups...