Overview
ABSTRACT
Bacterial resistance to antibiotics is a global major public health issue. Silver nanoparticles, metal oxides or nanocarbones could be an alternative to antibiotics. The antimicrobial effect of nanoparticles is inversely proportional to their size. Indeed at nanoscale, particles have greater efficiency in comparison with identical materials of greater size. The medical application of nanoparticles is possible for certain nanoparticles that are cytotoxic against bacteria but not against mammalian cells.
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Jasmina VIDIC: Research engineer at the French National Institute for Agronomic Research (INRA), Virology and Molecular Immunology Laboratory, Jouy-en-Josas. She is in charge of the biophysics platform and is her team's main contact for the C'Nano-Île-de-France network. [email protected]
INTRODUCTION
Bacterial resistance to antibiotics is a major public health problem. Nanoparticles of silver, metal oxides and nanocarbons could provide an alternative to antibiotics. The antimicrobial effect of nanoparticles is inversely proportional to their size. Indeed, at the nanometric scale, nanoparticles are more effective than the same materials of larger size. Some nanoparticles are cytotoxic against microbes, but not against mammalian cells.
Resistance to antibiotics in bacteria represents a worldwide public health problem. Silver nanoparticles, metal oxides or nanocarbons can be an alternative to antibiotics. The antimicrobial efficacy of the nanoparticles is inversely correlated with their size. At nanoscale particles have improved specificity and efficiency compared to the same materials of greater size. The medical application of nanoparticles is possible because some nanoparticles are cytotoxic against bacteria but not against mammalian cells.
antimicrobial activity, metal oxides, silver nanoparticles, nanotubes, mechanisms of action, titanium dioxide nanoparticles, environmental toxicity.
antimicrobial activity, metal oxides, silver nanoparticles, nanotubes, mechanism of action, titanium dioxide nanoparticles, environmental toxicity.
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Nanoparticles for antibacterial, antifungal and antiviral applications
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