Reproductive toxicity
Industrial Toxicology
Quizzed article REF: SE1605 V3
Reproductive toxicity
Industrial Toxicology

Author : Alain LOMBARD

Publication date: May 10, 2021, Review date: May 31, 2021 | Lire en français

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9. Reproductive toxicity

There are two types of action:

  • on male or female fertility;

  • on the foetus (teratogenesis).

9.1 Action on fertility

Chemicals and drugs can act directly on the CNS, particularly the hypothalamus and adenohypophysis, and disrupt libido (impotence), erection and ejaculation, or spermatogenesis by acting on the testicles (atrophy) or producing functional sperm abnormalities (figure 12 ), or acting on DNA and creating genetic and chromosomal aberrations.

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