2. Routes of entry into the body
2.1 Lungs
The lungs are the main route of entry for xenobiotics (substances foreign to the body). They are characterized by :
large exchange surface area: alveolar surface area ≥ 100 to 150 m 2 ;
a thin alveolar wall and strong vascularization;
a high volume of gas exchange.
The volume of air inspired by physical activity for workers is :
at rest ≥ 6 L/min ;
during moderate work ≥ 20 L/min ;
during intense work ≥ 100 L/min.
To determine human...
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Routes of entry into the body
Bioavailability in the body
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...Regulations
Regulation (EC) No 1272/2008 of the European Parliament and of the Council of December 16, 2008 on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 (see various amendments).
Arrêté du 7 décembre 2009 (JO du 16 décembre 2009, 3 pages): modification des arrêtés du 20 avril 1994 et...
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