Practical sheet | REF: FIC1181 V1

Actions of ultrafine particles (UFP) on the body: nanomaterials (NM)

Author: Alain LOMBARD

Publication date: December 10, 2014, Review date: September 9, 2025 | Lire en français

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2. How do nanomaterials enter the body?

Several penetration routes are possible: pulmonary, cutaneous and digestive.

2.1 Pulmonary penetration

Particulate nanomaterials are deposited in the pulmonary tract by the same process as micrometric particles. However, their aerodynamic behavior does not follow the laws that govern micrometric particles (see Absorption-Distribution-Metabolization-Excretion (ADME): how does a chemical substance circulate in the body? [FIC 1168] ), leading to...

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How do nanomaterials enter the body?