5. How are eye irritation tests conducted?
5.1 In vivo" test on albino rabbit eyes
OECD test no. 405: Acute irritant/corrosive effect on eyes.
Application of 0.1 g of product in the conjunctival cul-de-sac of one eye of three albino rabbits. The second eye served as a control.
Rating of the intensity of effects according to a scale (erythema and palpebral edema, congestion of the iris and corneal abrasion)
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How are eye irritation tests conducted?
In vitro" eye irritation or corrosion tests
Bibliography
A. Lombard et al. – Techno-economic evaluation of products in the early stages of development. Part 2, pp. 153-281. ISTE Éditions, Ltd London (2024).
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