Overview
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Alain LOMBARD: Consultant toxicologist and IPRP, Allotoxconsulting, Antibes, France
INTRODUCTION
The aim of this data sheet is to help you recognize and assess the allergenic potential of a chemical substance.
Sensitization to a chemical substance occurs after repeated, low-dose contact over a varying period of time. Sensitization reactions (allergy) are triggered unexpectedly by a new incidental contact with the sensitizing substance.
The role of the health and safety officer is to identify sensitizing substances, assess their hazards and prevent risks. This requires an understanding of sensitization mechanisms, and the ability to interpret study results.
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Bibliography
A. Lombard et al. – Techno-economic evaluation of products in the early stages of development. Part 2, pp. 153-281. ISTE Éditions, Ltd London (2024).
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The OECD provides guidelines for the testing of chemicals, including a set of the most relevant internationally-agreed test methods used by governments, industry and independent laboratories to determine the safety of chemicals and preparations, including pesticides and industrial chemicals. They cover tests on the physico-chemical properties of substances,...
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