8. How valid are test results?
Irritation and corrosion tests must be carried out in accordance with international guidelines (OECD) and in laboratories working to Good Laboratory Practice (GLP/GLP) and using standardized procedures (SOP) (see Principles of Industrial and Regulatory Toxicology
The "in vivo" skin irritation test is performed on albino rabbits, whose skin is not colored and is thinner than that of humans. In addition, chemical substances are applied under a semi-occlusive dressing that keeps the substance in close contact with the skin...
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How valid are test results?
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Bibliography
A. Lombard et al. – Techno-economic evaluation of products in the early stages of development. Part 2, pp. 153-281. ISTE Éditions, Ltd London (2024).
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