6. How do chemicals enter the nervous system?
The physico-chemical properties of xenobiotics facilitate their penetration across the brain barrier.
6.1 Size: low molecular weight and small size substances
Nanomaterials smaller than 50 nanometers (0.05 microns) reach the brain, particularly the olfactory bulb, by migrating along the olfactory nerves from the olfactory epithelium in the nose, as viruses do.
Chemicals with low molecular weight and steric hindrance can pass through membrane channels.
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How do chemicals enter the nervous system?
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A. Lombard et al (2024), part 2 pp 153-281, Techno-economic evaluation of products at the initial stage of development, ISTE éditions Ltd London.
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