Mistakes to avoid
Systemic toxicity: target organs, nervous system
Practical sheet REF: FIC1176 V1
Mistakes to avoid
Systemic toxicity: target organs, nervous system

Author : Alain LOMBARD

Publication date: May 10, 2025 | Lire en français

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10. Mistakes to avoid

10.1 Don't neglect the physico-chemical data of your substances

Important data are :

  • molecular weight, steric hindrance, volatility (boiling point, PKa, log Po/w) ;

  • conf: sheet no. 1167.

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10.2 Don't neglect clinical observations in toxicology studies

Look for observations of clinical signs of neurotoxicity in test animals in studies involving all routes of administration (inhalation, gavage and...

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