10. Mistakes to avoid
10.1 Don't neglect the physico-chemical data of your substances
Important data are :
molecular weight, steric hindrance, volatility (boiling point, PKa, log Po/w) ;
conf: sheet no. 1167.
10.2 Don't neglect clinical observations in toxicology studies
Look for observations of clinical signs of neurotoxicity in test animals in studies involving all routes of administration (inhalation, gavage and...
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Bibliography
A. Lombard et al (2024), part 2 pp 153-281, Techno-economic evaluation of products at the initial stage of development, ISTE éditions Ltd London.
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