5. Local action
Nanodrug routes of administration vary widely. Although most formulations on the market have been designed for the parenteral route (particularly intravenous), they can also be administered via the ocular, nasal, oral, cutaneous, digestive or pulmonary routes. For these routes, nanomedicines can be retained locally, releasing the active substance in situ. However, epithelial or skin barriers are not always impenetrable. A certain quantity of nanoparticles may be absorbed through these barriers (figure 4 ). The drug's action then changes from a local to a systemic effect, as the particles enter the bloodstream and are then transported to the tissues in what is known as the distribution phase (figure
Exclusive to subscribers. 97% yet to be discovered!
Already subscribed? Log in!
Local action
Systemic action
Article included in this offer
"Nanosciences and nanotechnologies"
(
137 articles
)
Updated and enriched with articles validated by our scientific committees
A set of exclusive tools to complement the resources
Bibliography
Exclusive to subscribers. 97% yet to be discovered!
Already subscribed? Log in!
