6. Various fluoridation methods
Apart from the major fluorination processes discussed above, there are many other methods and reagents for introducing a fluorine atom into a molecule. Some of these techniques have found industrial applications (preparation of aromatic fluorinated products by the diazotization method), but most are merely laboratory methods which could nevertheless be of interest for the preparation of particularly complex compounds, used for example in the pharmaceutical field.
6.1 Diazotization method
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Aromatic derivatives containing one or two fluorine atoms (mono- and difluorobenzenes, monofluorotoluenes, etc.) are prepared industrially by diazotizing the corresponding amines in HF medium and decomposing the resulting diazonium fluorides in situ:...
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Various fluoridation methods
Preparation of fluorinated products by transformation of other fluorinated derivatives
References
Theses
- - http://www.sudoc.abes.fr
- LOUSTAUNAU (A.) - Fluoration d'hydrocarbures chlorés en phase gazeuse en présence de catalyseurs à base d'oxyde de chrome : effet de l'ajout de dopant. - Université de Poitiers. Faculté...
Comments on the bibliography
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Apart from the classic chemistry encyclopedias :
KIRK-OTHMER Encyclopedia of Chemical Technology. 2004 Wiley Publishers.
ULLMANN's Encyclopedia of industrial Chemistry 2004 Wiley Verlag.
which each devote an important chapter to organic fluorine derivatives, the first...
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