1. Home
  2. Environment - Safety
  3. Chemical risk prevention manager

  4. Determining DMEL

Practical sheet | REF: FIC1457 V2

Determining DMEL

Author: Alain LOMBARD

Publication date: November 10, 2025 | Lire en français

You do not have access to this resource.
Click here to request your free trial access!

Already subscribed? Log in!

Automatically translated using artificial intelligence technology (Note that only the original version is binding) > find out more.

    A  |  A

    Overview

    Read this article from a comprehensive knowledge base, updated and supplemented with articles reviewed by scientific committees.

    Read the article

    AUTHOR

    • Alain LOMBARD: Toxicologist and risk management consultant, Allotoxconsulting, Antibes, France

     INTRODUCTION

    Producers and importers of a chemical substance must define DMELs in the REACh dossier in order to protect workers, consumers, and the general population potentially exposed to the chemical substance from mutagenic and carcinogenic risks.

    DMELs must be defined for several types of populations: workers, consumers, and humans via the environment.

    This fact sheet will help you understand how DMELs are calculated and defined, as well as their impact on the substance to which they apply.

    You do not have access to this resource.

    Exclusive to subscribers. 97% yet to be discovered!

    You do not have access to this resource.
    Click here to request your free trial access!

    Already subscribed? Log in!

    The Ultimate Scientific and Technical Reference

    A Comprehensive Knowledge Base, with over 1,200 authors and 100 scientific advisors
    + More than 10,000 articles and 1,000 how-to sheets, over 800 new or updated articles every year
    From design to prototyping, right through to industrialization, the reference for securing the development of your industrial projects

    EDITIONS

    Other editions of this article are available:

    Feb, 2015 archived version 1 by Alain LOMBARD

    This article is included in

    Chemical risk prevention manager

    This offer includes:

    Knowledge Base

    Updated and enriched with articles validated by our scientific committees

    Services

    A set of exclusive tools to complement the resources

    Practical Path

    Operational and didactic, to guarantee the acquisition of transversal skills

    Doc & Quiz

    Interactive articles with quizzes, for constructive reading

    Subscribe now!

    Ongoing reading
    Determination of DMELs (derived minimal effect levels)
    Outline