What are endocrine disruptors (EDs)?
Specific systemic toxicity: endocrine disruptors (EDs)
Practical sheet REF: FIC1180 V1
What are endocrine disruptors (EDs)?
Specific systemic toxicity: endocrine disruptors (EDs)

Author : Gautier VINCENT

Publication date: October 10, 2022 | Lire en français

Logo Techniques de l'Ingenieur You do not have access to this resource.
Request your free trial access! Free trial

Already subscribed?

2. What are endocrine disruptors (EDs)?

According to the WHO definition in 2012: "An endocrine disruptor is an exogenous substance or mixture that alters the functions of the endocrine system and thus induces adverse health effects in an intact organism, its progeny or subpopulations".

Endocrine disruptors act in three different ways.

  • Mimetic (or agonist) effect: imitation of the action of a natural hormone (like a false key in the "biological locks" that exist in organs and cells).

  • Blocking effect (or antagonist): blocking the action of a natural hormone (by saturating cell receptors, for example).

  • Disruptive (or interference) effect: disruption, i.e. hindrance or blockage of the production, transport or metabolism of hormones or receptors, induced by abnormal hormonal action in the body...

You do not have access to this resource.
Logo Techniques de l'Ingenieur

Exclusive to subscribers. 97% yet to be discovered!

You do not have access to this resource. Click here to request your free trial access!

Already subscribed?


Article included in this offer

"Chemical risk prevention manager"

( 219 articles )

Complete knowledge base

Updated and enriched with articles validated by our scientific committees

Services

A set of exclusive tools to complement the resources

View offer details
Contact us