What are the consequences of toxic liver damage?
Systemic toxicity: target organ, liver
Practical sheet REF: FIC1174 V1
What are the consequences of toxic liver damage?
Systemic toxicity: target organ, liver

Author : Alain LOMBARD

Publication date: May 10, 2025 | Lire en français

Logo Techniques de l'Ingenieur You do not have access to this resource.
Request your free trial access! Free trial

Already subscribed?

4. What are the consequences of toxic liver damage?

Toxic liver damage is characterized by a sharp increase in liver biomarkers in the blood:

  • isolated or predominant increase in transaminases, particularly ASpartate-AminoTransferase (ASAT);

  • increased alkaline phosphatase ;

  • isolated increase in Gamma-GlutamylTransferase (GGT).

Liver damage also leads to structural changes in the liver, visible on histological examination.

4.1 Acute exposure to ethanol

This exhibition leads to :

  • an accumulation of lipids in the cells (steatosis);

  • hepatic necrosis;

  • ...

You do not have access to this resource.
Logo Techniques de l'Ingenieur

Exclusive to subscribers. 97% yet to be discovered!

You do not have access to this resource. Click here to request your free trial access!

Already subscribed?


Article included in this offer

"Chemical risk prevention manager"

( 219 articles )

Complete knowledge base

Updated and enriched with articles validated by our scientific committees

Services

A set of exclusive tools to complement the resources

View offer details
Contact us