Glossary
Amorphous and glassy states of molecular and pharmaceutical compounds Applications and uses

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Glossary


Amorphous and glassy states of molecular and pharmaceutical compounds Applications and uses

Author : Marc DESCAMPS

Publication date: April 10, 2020 | Lire en français

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13. Glossary

supersaturation; supersaturation

State of a solution containing a quantity of dissolved substance greater than that corresponding to the solubility limit of the crystallized substance. Dissolution of the amorphous form of a substance can lead to supersaturation, enabling high concentrations to be obtained in solution.

amorphous solid dispersion; Amorphous Solid Dispersion (ASD)

In the pharmaceutical field, amorphous, solid, single-phase, two-component PA-polymer systems. In this glassy solid solution, the PA molecules are dispersed in the amorphous polymer matrix to give a mixture that is statistically homogeneous at the molecular level.

co-amorphous; co-amorphous system

Homogeneous amorphous solid dispersion of a PA molecule and another "small" (non-polymeric) molecule....

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