Model building and evaluation
Pharmacometry
Article REF: PHA1010 V1
Model building and evaluation
Pharmacometry

Authors : Caroline BAZZOLI, Julie BERTRAND, Emmanuelle comets

Publication date: June 10, 2014, Review date: May 29, 2020 | Lire en français

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4. Model building and evaluation

Model building in a pharmacometrics analysis requires proposed models to be evaluated, and compared statistically. In this section, we present the inference and diagnostic tools used to conduct this decision-making process .

4.1 Inference

  • Maximum likelihood inference

    In regression, the classic inference tests are the likelihood ratio test (LRT), the Wald test and the score...

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