1. Laboratory-tested efficacy

Tests of active ingredient efficacy and penetration can be carried out on operative waste, in which case they are referred to as "ex vivo" tests, or on in vitro cell culture models, which are as close as possible to real-life conditions: models of stressed, functionalized, two- or three-dimensional skin.... The role of cell and tissue engineering in cosmetology is crucial for understanding physiological and pathological mechanisms, and proposing innovative therapies.

1.1 Regulatory framework

Constraints on tests carried out on human cells in laboratories concern the recovery of surgical waste: such waste comes from surgical procedures and can be stored in "biobanks", or used directly...

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Laboratory-tested efficacy

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Clinical objectivation of cosmetic efficacy

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Bibliography

(1) - VIENNET (C.), BRIDE (J.), COHEN-LETESSIER (A.), HUMBERT (P.) - Mechanical behavior of fibroblasts included in collagen lattices. - J Soc Biol. ; 195(4):427-3 (2001).
(2) - ROLIN (G.), PLACET (V.), JACQUET (E.), TAUZIN (H.), ROBIN (S.), PAZART (L.), VIENNET (C.),...

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