13. Glossary
ADME (Absorption – Distribution – Metabolization – Excretion) :
Xenobiotic fate in the body.
Bioavailability; biodisponibility
Form, concentration and lifetime of a xenobiotic in the body.
Clastogenesis; clastogenesis
Chemical or physical action likely to cause breaks or deletions in a DNA molecule, creating a chromosomal aberration.
Concentration létale; lethal concentration
Concentration of a toxic substance that causes the death of a percentage of individuals in a given population, over a given period of time, when exposed to this toxic substance.
Demi-vie ;half life
Time required to eliminate half the amount of xenobiotic in the body.
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