Synthetic molecules
Applying NMR to structure determination

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P1092 V1 Article

Synthetic molecules


Applying NMR to structure determination

Author : Nicole PLATZER

Publication date: September 10, 2002 | Lire en français

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3. Synthetic molecules

In what follows, it will be assumed that the spectra have been analyzed by the basic experiments, which will no longer be systematically commented on.

3.1 Determination of stereochemistry by NOE

The diagram below shows the expected stereochemistry of molecule 4. We need to check the opening of the epoxide and specify the relative stereochemistry of sites 7, 8, 8a . The couplings do not allow this.

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