4. Interference
4.1 Interference description
Like all analytical techniques, ICP-MS is not immune to a certain number of interferences, which are one of the limits to its analytical performance.
Two types of interference can be identified:
non-spectral interference due to matrix effects, which cause the signal to decrease or increase to varying degrees;
spectral interference, where the signal from the mass under analysis is overlapped by the signal from another isotope or molecular ion with a mass-to-charge ratio that is too close.
Non-spectral interferences are not characteristic of ICP-MS, as many are also observed in ICP-OES and even...
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Interference
Analytical performance
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