4. Separation of molecular solutes
4.1 Adsorption chromatography
Adsorption chromatography, also known as liquid-solid chromatography (LSC), uses silica and alumina gels as stationary phases.
It is well suited to the separation of compounds with different polar functional groups (as in the case of many therapeutic molecules) and positional isomers.
SCROLL TO TOPWe will only describe silica gels here, which are the stationary phases most commonly used in CLS.
A silica...
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Separation of molecular solutes
Separation of ionized solutes
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