7. Toxicology, environment, hygiene, analysis
7.1 Non-toxicity of plasticizers
Plasticizers have often given rise to controversy in the field of toxicology, as they are used in flexible PVCs to come into contact with food (meat and cheese packaging, soft drink capsules, etc.) or blood for transfusion. The most pessimistic calculations lead to possible intakes of 2.2 g DOA and 13 to 20 mg DOP per person per year.
All animal tests (on rats, mice, hamsters, dogs and primates) involved much higher ingested doses, the effects of which were very different from one species to another. Subchronic toxicity (no observable effect on all the species mentioned) was not observed for doses below 50 mg/kg per day for DOP and 150 mg/kg per day for DINP and DIDP. The same applies to alterations in reproductive mechanisms...
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Toxicology, environment, hygiene, analysis
References
- (1) - SEARS (J.K.), DARBY (J.R.) - The technology of plasticizers. - Willey & Sons Ed., 1 166 p. (ouvrage encyclopédique donnant près de 1 500 références sur 240 p. et décrivant les propriétés physiques de l'ensemble des plastifiants utilisés aujourd'hui et les propriétés des produits plastifiés) (1982).
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Standardization
- Plastiques et ébonite. Détermination de la dureté par pénétration au moyen d'un duromètre (Dureté Shore) (indice de classement : T 51-109). - NF ISO 868 - 9-86
- Plastiques. Détermination de la rigidité en torsion des plastiques souples. Partie 1 : Méthode générale (indice de classement : T 51-102). - NF ISO 458 /1 - 9-86
NF: French standards published by AFNOR (Association Française de Normalisation)....
Main suppliers of phthalates (and their brand names)
BASF AG (Palatinate) – BASF (Cie française).
Exxon Chemical Co. (Jayflex ) – Exxon Chemical France.
Hüls AG (Vestinol ) – Hüls France.
ICI Ltd (Hexaplast ) – ICI France SA.
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