How do chemicals enter the nervous system?
Systemic toxicity: target organs, nervous system

Add to my library

FIC1176 V1 Practical sheet

How do chemicals enter the nervous system?


Systemic toxicity: target organs, nervous system

Author : Alain LOMBARD

Publication date: May 10, 2025 | Lire en français

Add to my library Add to my library

Logo Techniques de l'Ingenieur You do not have access to this resource.
Request your free trial access! Free trial

Already subscribed?

6. How do chemicals enter the nervous system?

The physico-chemical properties of xenobiotics facilitate their penetration across the brain barrier.

6.1 Size: low molecular weight and small size substances

  • Nanomaterials smaller than 50 nanometers (0.05 microns) reach the brain, particularly the olfactory bulb, by migrating along the olfactory nerves from the olfactory epithelium in the nose, as viruses do.

  • Chemicals with low molecular weight and steric hindrance can pass through membrane channels.

SCROLL TO TOP

You do not have access to this resource.
Logo Techniques de l'Ingenieur

Exclusive to subscribers. 97% yet to be discovered!

You do not have access to this resource. Click here to request your free trial access!

Already subscribed?


Article included in this offer

"Safety and risk management"

( 463 articles )

Complete knowledge base

Updated and enriched with articles validated by our scientific committees

Services

A set of exclusive tools to complement the resources

View offer details
WhitePaper VLEP et exposition aux produits chimiques
19 October 2016
VLEP et exposition aux produits chimiques

Découvrez dans ce livre blanc comment les Valeurs Limites d’Exposition Professionnelle (VLEP) sont déterminées et comment optimiser le mesurage de l’exposition ...

Tous les livres blancs
Toutes les actualités
Contact us