Article | REF: RE115 V1

AFM techniques for observing nucleic acids and nucleoprotein complexes

Authors: Loïc HAMON, Patrick A. curmi, David PASTRE

Publication date: September 10, 2008 | Lire en français

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    AUTHORS

    • Loïc HAMON

    • Patrick A. curmi

    • David PASTRE

     INTRODUCTION

    In a biomolecular imaging system such as atomic force microscopy (AFM), where several partners interact - in this case the substrate surface, DNA and possibly proteins - it is essential to establish theoretically and experimentally the conditions for obtaining biologically relevant information about the interaction between the biomolecules themselves.

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    AFM techniques for observing nucleic acids and nucleoprotein complexes