2. Designing nanotechnology tools for therapeutic and diagnostic applications
The design of such nanotechnology-based tools is a complex process. It requires mastery of synthesis methods and the physico-chemical, biopharmaceutical and pharmacological characterization of nano-sized objects. The design of nanomedicines must also take into account the constraints imposed by the development of any pharmaceutical system intended for human administration.
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Thus, nanovectors proposed for therapeutic or diagnostic applications in vivo must necessarily meet two main criteria:
the materials of which they are made must be biodegradable (or easily eliminated from the body), and they must not induce toxic reactions;
they must be able to be loaded with active ingredients (or contrast agents) and transported, then released, to the biological target....
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Designing nanotechnology tools for therapeutic and diagnostic applications
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