Article | REF: PHA1007 V1

Preferred chemical structures for therapeutic activities

Author: Pascal COUDERT

Publication date: September 10, 2014 | Lire en français

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    2. Imidazole and triazole derivatives

    The family of azole derivatives includes compounds with a wide variety of therapeutic activities (figure 3 ), and it may seem difficult at first sight to predict what type of properties a newly synthesized imidazole or triazole compound will display simply by examining its structural formula. Nevertheless, a careful analysis of the various groups attached to the azole rings enables us to define its potential activity profile fairly precisely.

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