Article | REF: PHA1007 V2

Vector privileged chemical structures of therapeutic activities

Author: Pascal COUDERT

Publication date: March 10, 2024 | Lire en français

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    11. Other preferred chemical structures

    Some structural motifs are only found in a single therapeutic class, and are the vectors of a very specific pharmacological activity. This is the case for several families of antibiotics, non-steroidal anti-inflammatories, local anesthetics, bone resorption inhibitors, calcium antagonists and alkylating antitumor agents.

    11.1 Beta-lactams, quinolones and aminoglycosides with antibiotic activity

    • Beta-lactams are antibiotic substances with a β-lactam nucleus (figure 22 ), grouped into two families: penicillins and cephalosporins.

      The first compounds of natural origin, which could only be...

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