1. Solid phase extraction
1.1 Principle
Liquid-solid extraction is based on the distribution of compounds between the liquid phase (sample) and the solid phase (chosen adsorbent). To a first approximation, it is a process similar to elution chromatography, using the adsorbent as the stationary phase: if the solute has a strong affinity for the adsorbent, it remains totally bound to it during percolation of the aqueous sample (figure 1 ). The solute is then desorbed by a small volume of eluting solvent.
Knowledge of the retention mechanisms involved in liquid chromatography can therefore be directly transposed to this extraction technique, facilitating method development.
The Ultimate Scientific and Technical Reference
This article is included in
Analysis and Characterization
This offer includes:
Knowledge Base
Updated and enriched with articles validated by our scientific committees
Services
A set of exclusive tools to complement the resources
Practical Path
Operational and didactic, to guarantee the acquisition of transversal skills
Doc & Quiz
Interactive articles with quizzes, for constructive reading
Solid phase extraction
Coupling mode
References
Some recent theses
Training — Documentation
-
Internship
"Sample processing", http://www.espci.fr/recherche/labos/leca/traitement.htm
Technical data
Tables 1 and 2 give some technical data on the phases currently on the market and the suppliers from whom...
The Ultimate Scientific and Technical Reference
