Archive | REF: FIC1184 V1

Determining toxicological reference values (TRVs)

Author: Alain LOMBARD

Publication date: May 10, 2015 | Lire en français

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    1. What are TRVs?

    A TRV is a toxicological value defined to quantify a risk to human health from respiratory exposure, depending on the duration of exposure (acute, subchronic or chronic). These values apply to the population as a whole, including sensitive population categories (children, pregnant women, the elderly, the sick).

    Please note

    Acute and chronic TRVs can also be defined for the oral route, in the case of food poisoning, but this is not the subject of this data sheet.

    1.1 Definition

    TRVs are defined for all possible accidental or fugitive inhalation exposures. A distinction is made between :

    • the acute TRVs (TRV/A) defined in the industrial context...

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