5. Methods for characterizing endocrine disruptors

5.1 In silico" or crystallographic methods

They involve the study of structure-activity relationships (QSAR) and the modeling of ligand-receptor binding.

The QSAR (Quantitative Structure Activity Relationship) method is the establishment of a quantitative relationship between a chemical structure and an activity in the form of chemical reactivity or biological activity. For example, the presence of benzene rings with an HO function in the chemical structure, as in the case of estradiol (figure 7...