3. Precursors and metabolites
A precursor (M-P) is a compound prepared from an active drug (M) to which a product (P) is attached, in order to modify its physico-chemical characteristics (stability, solubility, lipophilicity...) and improve its pharmacokinetic properties. After administration, bioconversion of the precursor leads to regeneration of the initial constituents, following chemical or enzymatic transformation [12] (figure 11 ).
Precursors are different from the metabolites formed from a drug, which may or may not have the same pharmacological properties as the drug itself.
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Precursors and metabolites
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References
Books dealing with the structure and/or preparation, therapeutic indications of drugs or active ingredients:
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