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Archive | REF: PHA2018 V1

Ophtalmic Preparations

Authors: Denis BROSSARD, Sylvie CRAUSTE-MANCIET

Publication date: December 10, 2014, Review date: November 30, 2023 | Lire en français

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    4. Eye drops

    4.1 Solutions

    Eye drops are the most widely used ophthalmic form, and a very large number of ophthalmic forms are marketed as solutions.

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    4.1.1 Formulation

    Formulation involves a number of excipients linked to the characteristics of the solution form and the active ingredient. For the latter, the essential points to study are its solubility, pH of solubility/stability in solution, osmotic activity and stability in solution. The main formulation steps involve dissolution/solubilization, adjustment...

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