Advanced therapy drugs
Ophtalmic Preparations
Article REF: PHA2018 V2
Advanced therapy drugs
Ophtalmic Preparations

Authors : Denis BROSSARD, Sylvie CRAUSTE-MANCIET

Publication date: July 10, 2025 | Lire en français

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10. Advanced therapy drugs

The latest therapeutic developments in cell and gene therapy are opening up new prospects in many fields, including ophthalmology.

10.1 Cell therapy

Tissue engineering and cell therapy are emerging disciplines that combine the use of biomaterials and cell biology to repair or regenerate biological tissues. The principle is based on the development of a polymeric network to support the growth of cells and/or bio-active molecules to build a tissue with characteristics close to those of the original tissue, in order to repair or renew damaged tissue.

In ophthalmology, developments concern the regeneration of ocular surfaces such as the cornea or limbus. The principle is based on ex vivo cell culture, for example of human conjunctival...

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