Supercritical fluids in chromatography
Supercritical Fluid Chromatography

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Supercritical fluids in chromatography


Supercritical Fluid Chromatography

Author : Didier THIÉBAUT

Publication date: September 10, 2016, Review date: October 1, 2021 | Lire en français

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1. Supercritical fluids in chromatography

Historical overview

As early as 1962, Klesper, Corwin and Turner used SPC for the separation of non-volatile porphyrins. However, the development of this method was initially overshadowed by that of liquid chromatography (LC), although examples of its use and developments were periodically published. It wasn't until 1982 that interest in SPC was revived, 1988 saw the publication of the first book

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