What is the impact of an irritant chemical on the respiratory tract?
Respiratory irritation, eye irritation, skin irritation: how does the localized action of chemical substances affect the body?
Practical sheet REF: FIC1170 V1
What is the impact of an irritant chemical on the respiratory tract?
Respiratory irritation, eye irritation, skin irritation: how does the localized action of chemical substances affect the body?

Author : Alain LOMBARD

Publication date: February 10, 2025 | Lire en français

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1. What is the impact of an irritant chemical on the respiratory tract?

The respiratory tract is the first route of contact and entry of toxic substances into the body.

1.1 Irritation of the nasal passages

Two effects are possible.

  • Irritation of the mucous membranes of the nasal cavity by acidic or basic chemicals (HCL, acrylates...) leads to inflammation (erythema), swelling (edema), hypersecretion of mucus (rhinorrhea), nasal obstruction, sneezing and headaches.

  • Degeneration of the olfactory epithelium can also occur, as a result of damage to the olfactory epithelium. It is a partial or total abrasion of the cells of the olfactory epithelium, and degeneration of the olfactory nerve that leads to the olfactory bulb in the brain. The result is a...

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