1. What is the impact of an irritant chemical on the respiratory tract?
The respiratory tract is the first route of contact and entry of toxic substances into the body.
1.1 Irritation of the nasal passages
Two effects are possible.
Irritation of the mucous membranes of the nasal cavity by acidic or basic chemicals (HCL, acrylates...) leads to inflammation (erythema), swelling (edema), hypersecretion of mucus (rhinorrhea), nasal obstruction, sneezing and headaches.
Degeneration of the olfactory epithelium can also occur, as a result of damage to the olfactory epithelium. It is a partial or total abrasion of the cells of the olfactory epithelium, and degeneration of the olfactory nerve that leads to the olfactory bulb in the brain. The result is a...
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What is the impact of an irritant chemical on the respiratory tract?
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Bibliography
A. Lombard et al. – Techno-economic evaluation of products in the early stages of development. Part 2, pp. 153-281. ISTE Éditions, Ltd London (2024).
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